Israel says it has struck almost all of Iran’s military infrastructure inside Syria in its biggest assault since the start of the civil war there.
The strikes came after 20 rockets were fired at Israeli military positions in the occupied Golan Heights overnight.
Syria’s military said the Israeli “aggression” had killed three people.
There was no immediate comment from Iran, whose deployment of troops to Syria to help President Bashar al-Assad has alarmed Israel.
Iran has repeatedly called for an end to the existence of the Jewish state.
Russia, Germany and France called on both countries to exercise restraint, but the US said Iran bore “full responsibility for the consequences of its reckless actions” and that Israel had a right to defend itself.
The Israel Defence Forces (IDF) said that early on Thursday morning 20 rockets had been launched at its forward posts there by the Quds Force, the overseas operations arm of Iran’s Islamic Revolution Guards Corps.